Linda A Schuler Selected Research

Prolactin Receptors (Prolactin Receptor)

1/2017	Elevated collagen-I augments tumor progressive signals, intravasation and metastasis of prolactin-induced estrogen receptor alpha positive mammary tumor cells.
12/2013	Prolactin activates ERα in the absence of ligand in female mammary development and carcinogenesis in vivo.
2/2009	SRC family kinases accelerate prolactin receptor internalization, modulating trafficking and signaling in breast cancer cells.
10/2005	Proteasomes mediate prolactin-induced receptor down-regulation and fragment generation in breast cancer cells.
12/2004	Multiple kinase cascades mediate prolactin signals to activating protein-1 in breast cancer cells.
1/2004	Endogenous human prolactin and not exogenous human prolactin induces estrogen receptor alpha and prolactin receptor expression and increases estrogen responsiveness in breast cancer cells.

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Linda A Schuler Research Topics

Disease

32	Breast Neoplasms (Breast Cancer) 01/2022 - 04/2002
27	Neoplasms (Cancer) 01/2022 - 07/2003
8	Carcinoma (Carcinomatosis) 10/2021 - 02/2003
8	Carcinogenesis 01/2015 - 07/2005
4	Neoplasm Metastasis (Metastasis) 10/2019 - 05/2013
3	Adenocarcinoma 10/2018 - 04/2006
1	Disease Progression 01/2022
1	Hyperplasia 10/2021
1	Triple Negative Breast Neoplasms 07/2021
1	Circulating Neoplastic Cells 01/2017
1	Neoplastic Processes 10/2009
1	Breast Diseases (Breast Disease) 04/2008
1	Lymphoma (Lymphomas) 02/2004

Drug/Important Bio-Agent (IBA)

31	ProlactinIBA 01/2022 - 02/2003
12	Estrogens (Estrogen)FDA Link 07/2021 - 01/2004
12	Estrogen Receptor alphaIBA 07/2021 - 07/2003
8	Hormones (Hormone)IBA 01/2022 - 01/2004
7	Estrogen ReceptorsIBA 07/2021 - 07/2005
6	Prolactin Receptors (Prolactin Receptor)IBA 01/2017 - 01/2004
5	LigandsIBA 01/2019 - 10/2005
5	CollagenIBA 10/2018 - 05/2013
4	Estrogen Receptor Modulators (Antiestrogen)IBA 10/2019 - 12/2013
4	Fulvestrant (Faslodex)FDA Link 10/2018 - 01/2011
4	Phenobarbital (Luminal)FDA Link 01/2018 - 01/2011
4	Proteins (Proteins, Gene)FDA Link 01/2011 - 02/2004
3	Protein Isoforms (Isoforms)IBA 03/2018 - 10/2005
3	SteroidsIBA 10/2017 - 01/2008
3	Phosphotransferases (Kinase)IBA 01/2017 - 12/2004
3	STAT5 Transcription FactorIBA 12/2013 - 12/2004
3	Cyclin D1IBA 07/2012 - 04/2002
3	Transforming Growth Factor alpha (TGF-alpha)IBA 03/2009 - 04/2006
2	Biological ProductsIBA 07/2021 - 11/2010
2	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 10/2019 - 07/2005
2	Progesterone Receptors (Progesterone Receptor)IBA 01/2011 - 03/2009
2	LipocalinsIBA 01/2011 - 04/2006
2	Insulin-Like Growth Factor I (IGF-1)IBA 03/2010 - 04/2008
1	CateninsIBA 10/2021
1	Tamoxifen FDA LinkGeneric 10/2019
1	MTOR InhibitorsIBA 10/2018
1	Sirolimus (Rapamycin)FDA Link 10/2018
1	Pharmaceutical PreparationsIBA 01/2018
1	Green Fluorescent ProteinsIBA 01/2017
1	Janus KinasesIBA 01/2017
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2011
1	Non-Receptor Type 11 Protein Tyrosine PhosphataseIBA 03/2010
1	IGF Type 1 Receptor (IGF 1 Receptor)IBA 03/2010
1	TenascinIBA 10/2009
1	SERPIN-B5 (maspin)IBA 10/2009
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 03/2009
1	src-Family KinasesIBA 02/2009
1	Insulin-Like PeptidesIBA 04/2008
1	Androgen Receptors (Androgen Receptor)IBA 01/2008
1	Transcription Factors (Transcription Factor)IBA 07/2005
1	Janus Kinase 2IBA 12/2004
1	Complementary DNA (cDNA)IBA 02/2004
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 02/2004
1	PhosphoproteinsIBA 02/2004
1	Butyrates (Butyrate)IBA 02/2004
1	Asp(179)- prolactinIBA 12/2003
1	Coloring Agents (Dyes)IBA 07/2003

Therapy/Procedure

7	Therapeutics 10/2019 - 12/2003
2	Transplantation 10/2018 - 01/2017
2	Ovariectomy (Oophorectomy) 10/2009 - 03/2009
1	Castration 01/2008